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Updated: Feb 14, 2026

A Simple Cell-based Immunofluorescence Assay to Detect Autoantibody Against the N-Methyl-D-Aspartate NMDA Receptor in Blood
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Anti-NMDA receptor encephalitis presenting as postpartum psychosis-a clinical description and review

Mukku Shiva Shanker Reddy1, Harish Thippeswamy2, Sundarnag Ganjekar1

  • 1Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Hosur Road, Bangalore, 560029, India.

Archives of Women'S Mental Health
|February 9, 2018
PubMed

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is increasingly being recognised to be associated with protean neuropsychiatric manifestations. Anti-NMDAR encephalitis is considered to be the most common amongst the autoimmune-mediated encephalitic disorders. It is caused by the autoantibodies against GluN1 subunits of N-methyl-D-aspartate (NMDA) receptor and manifests with prominent psychiatric symptoms, especially during the initial phase of illness. Literature anti-NMDAR encephalitis presenting with postpartum psychosis is scant. In this report, we present a 28-year-old lady with postpartum psychosis as presenting manifestation of anti-NMDAR encephalitis and discuss the neuropsychiatric manifestations of this emerging entity.

Keywords:
Autoimmune encephalitisNMDA receptorNMDARPostpartumPsychosis

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