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Related Experiment Video

Updated: Feb 14, 2026

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3D printed Lego®-like modular microfluidic devices based on capillary driving.

Jing Nie1,2, Qing Gao1,2, Jing-Jiang Qiu1,2

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Summary

Researchers developed a novel modular microfluidic device using 3D printing and capillary force. This Lego-like system offers rapid assembly, leak-free connections, and versatile applications in chemical and biological research.

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Area of Science:

  • Microfluidics
  • 3D Printing
  • Biotechnology

Background:

  • Modular microfluidic devices face challenges with leaking and alignment.
  • Current assembly methods require significant effort and specialized techniques.

Purpose of the Study:

  • To present a novel, rapidly assembled modular microfluidic device.
  • To overcome limitations of traditional microfluidic assembly.

Main Methods:

  • Utilizing low-cost 3D printing for fabricating functional modules.
  • Employing capillary force for assembly, eliminating the need for strict seals or alignment.
  • Designing modules with unified standard interfaces for Lego-like integration.

Main Results:

  • Demonstrated a novel modular microfluidic device driven by capillary force.
  • Achieved simple, efficient manufacturing with controllable flow channel scales.
  • Successfully applied the device for stent degradation and cell cultures.

Conclusions:

  • The capillary-driven modular microfluidic system offers a simple, efficient, and versatile platform.
  • This approach has significant potential for diverse applications in chemical and biological research.
  • The Lego-like modularity enables rapid prototyping and customization.