Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Misdiagnosis and prevalence of rheumatological diseases in early inflammatory arthritis clinic: results from a UK single-centre retrospective cohort study.

EULAR rheumatology open·2026
Same author

Exploring biomarkers for treatment response in psoriatic arthritis: a focus on multi-omics technologies.

The pharmacogenomics journal·2026
Same author

Exploring the barriers and facilitators to accessing and engaging with information resources about rheumatoid arthritis (RA) by ethnic minority or non-native patients: A systematic review and thematic synthesis.

Patient education and counseling·2026
Same author

Molecular Biomarkers for Predicting Treatment Response in Psoriatic Arthritis.

Rheumatic diseases clinics of North America·2026
Same author

Transcriptomic profiling of secukinumab-treated psoriatic arthritis reveals potential novel response-associated pathways.

Rheumatology (Oxford, England)·2026
Same author

Inflammation response criteria for rheumatoid arthritis based on the two-component disease activity score.

RMD open·2026
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Buruli ulcer in Africa: between innovation and pragmatism.

Nature reviews. Disease primers·2026
Same journal

Author Correction: Atopic dermatitis.

Nature reviews. Disease primers·2026
See all related articles

Related Experiment Video

Updated: Feb 14, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

1.2K

Rheumatoid arthritis.

Josef S Smolen1, Daniel Aletaha1, Anne Barton2

  • 1Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

Nature Reviews. Disease Primers
|February 9, 2018
PubMed
Summary
This summary is machine-generated.

Rheumatoid arthritis (RA) is a chronic autoimmune disease impacting joints. Advances in understanding RA, including novel autoantibodies and targeted therapies, have significantly improved patient outcomes and management strategies over the last two decades.

More Related Videos

Generation of Induced-pluripotent Stem Cells Using Fibroblast-like Synoviocytes Isolated from Joints of Rheumatoid Arthritis Patients
09:31

Generation of Induced-pluripotent Stem Cells Using Fibroblast-like Synoviocytes Isolated from Joints of Rheumatoid Arthritis Patients

Published on: October 16, 2016

9.9K
Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis
06:31

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis

Published on: October 6, 2023

3.2K

Related Experiment Videos

Last Updated: Feb 14, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

1.2K
Generation of Induced-pluripotent Stem Cells Using Fibroblast-like Synoviocytes Isolated from Joints of Rheumatoid Arthritis Patients
09:31

Generation of Induced-pluripotent Stem Cells Using Fibroblast-like Synoviocytes Isolated from Joints of Rheumatoid Arthritis Patients

Published on: October 16, 2016

9.9K
Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis
06:31

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis

Published on: October 6, 2023

3.2K

Area of Science:

  • Immunology
  • Rheumatology
  • Internal Medicine

Background:

  • Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease primarily affecting joints.
  • RA is characterized by autoantibodies targeting self-epitopes, impacting diagnostic accuracy.
  • Understanding RA pathogenesis has led to targeted therapies and improved patient management.

Purpose of the Study:

  • To provide a comprehensive overview of Rheumatoid Arthritis (RA).
  • To discuss advancements in RA diagnosis and management.
  • To highlight the impact of new therapies and assessment tools on patient outcomes.

Main Methods:

  • Review of epidemiological data.
  • Discussion of pathophysiological mechanisms.
  • Analysis of diagnostic criteria and clinical assessment tools.
  • Evaluation of current and emerging therapeutic strategies.

Main Results:

  • Novel autoantibodies enhance diagnostic accuracy for RA.
  • Advanced assessment tools better characterize disease activity and progression.
  • Targeted disease-modifying antirheumatic drugs (DMARDs) have improved RA management.
  • A treat-to-target approach optimizes physical functioning and social participation.

Conclusions:

  • Significant progress in RA understanding and treatment over the past two decades.
  • Early diagnosis and effective, adaptive therapy are crucial for managing RA.
  • Current strategies aim for remission or low disease activity, preventing joint damage and improving quality of life.