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Updated: Feb 14, 2026

Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
Merkel Cell Carcinoma of the Cheek
Andrea Sisti1, Cesare Brandi, Luca Grimaldi
1Plastic and Reconstructive Surgery Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Italy.
Abstract:
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer with a neuroendocrine phenotype. Here, the authors reported a case of MCC, presented as a rapidly growing, asymptomatic, erythematous nodule measuring 3.8 cm × 2.8 cm in diameter on the right cheek of an 85-year-old Caucasian woman. After resection of the nodule, the defect was repaired with cutaneous graft taken from the supraclavicular area and healed uneventfully. Histopathologic examination confirmed the diagnosis of MCC.
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