Related Experiment Videos
[Histamine receptor-bearing lymphocytes. V. Induction of suppressor cells with histamine or concanavalin A]
Immature human T-lymphocytes form rosettes with autologous erythrocytes (A-RFC). Con A induced suppressor cells in fractions of A-RFC. Mature, immunocompetent T-lymphocytes are non-A-RFC. They bear histamine receptors, and in such fractions histamine induced suppressor cells. After activation, both suppressor cells seem to be identical. They bear histamine receptors, Fe-receptors for IgG and the T8-antigen. For the expression of their suppressive effect the presence of monocytes is required.
Immature human T-lymphocytes form rosettes with autologous erythrocytes (A-RFC). Con A induced suppressor cells in fractions of A-RFC. Mature, immunocompetent T-lymphocytes are non-A-RFC. They bear histamine receptors, and in such fractions histamine induced suppressor cells. After activation, both suppressor cells seem to be identical. They bear histamine receptors, Fe-receptors for IgG and the T8-antigen. For the expression of their suppressive effect the presence of monocytes is required.