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Updated: Feb 14, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Variation of Coma Aberration With Prismatic Soft Contact Lenses
Carlos Carpena-Torres1, José Manuel López-Alonso, Mercedes Burgos-Martínez
1Departments of Optics II (Optometry and Vision) (C.C.-T., G.C., J.C.-A.), and Optics I (J.M.L.-A.), Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain; and mark'ennovy Personalized Care (M.B.-M.), Madrid, Spain.
Purpose:
To analyze the variation in vertical coma and the rest of ocular aberrations before and after fitting prismatic soft contact lenses (PSCL).
Methods:
Thirty-seven eyes of 20 healthy subjects (24.30±2.03 years) were evaluated to analyze the variation in ocular wavefront aberrations before and after fitting PSCL of different base-down prism values (1.0, 1.5, and 2.0 prism diopters [PD]), designed to study its influence in the compensation of vertical coma aberration. A Hartmann-Shack sensor with a wavelength of 780 nm was used, considering a pupil size of 3 mm. In addition, the influence of PSCL in visual function under photopic conditions in terms of high-contrast visual acuity and contrast sensitivity was evaluated.
Results:
There was statistically significant differences (P<0.05) in ocular aberrations from first to seventh order after fitting PSCL, but only the differences in vertical tilt, horizontal tilt, defocus, vertical astigmatism, and vertical coma were clinically relevant (Strehl ratio <0.8). The mean of vertical coma (μm) was 0.022±0.030 for control, 0.045±0.064 for 1.0 PD (P=0.645), 0.048±0.053 for 1.5 PD (P=0.037), and 0.074±0.047 for 2.0 PD (P<0.001). The changes in visual function under photopic conditions were not clinically relevant.
Conclusions:
PSCL induce a magnitude of vertical coma aberration directly proportional to prism value without affecting the rest of ocular high-order aberrations.
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