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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.0K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

553
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
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[Perinatal tuberculosis].

Jessica Sáenz-Gómez1, José Karam Bechara1, Lourdes Jamaica Balderas1

  • 1Servicio de Neumología, Hospital Infantil de México Federico Gómez, México D.F., México.

Boletin Medico Del Hospital Infantil De Mexico
|February 9, 2018
PubMed
Summary

Perinatal tuberculosis, a severe neonatal infection, requires prompt suspicion due to nonspecific symptoms and high mortality. Maternal tuberculosis history is crucial for early diagnosis in infants with persistent pneumonia or sepsis.

Keywords:
MycobacteriumNeumoníaPerinatalPneumoniaTuberculosis

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Area of Science:

  • Neonatology
  • Infectious Diseases
  • Pediatric Tuberculosis

Context:

  • Perinatal tuberculosis is acquired during birth or the early neonatal period.
  • Diagnosis is challenging due to nonspecific symptoms mimicking other infections.
  • The condition has a high mortality rate, necessitating prompt medical suspicion.

Purpose:

  • To highlight the importance of diagnosing perinatal tuberculosis.
  • To present a case report of a neonate with fatal perinatal tuberculosis.
  • To emphasize the role of maternal history in diagnosis.

Summary:

  • A 3-month-old infant presented with persistent pneumonia unresponsive to antibiotics.
  • The infant's mother died of septic shock, later diagnosed as peritoneal tuberculosis post-mortem.
  • Molecular testing confirmed Mycobacterium tuberculosis in the infant, establishing a perinatal tuberculosis diagnosis.

Impact:

  • Suspect perinatal tuberculosis in infants with antibiotic-unresponsive sepsis or pneumonia.
  • Maternal tuberculosis history is a critical factor for orienting diagnosis.
  • Early diagnosis and intervention are vital to reduce the high mortality associated with perinatal tuberculosis.