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Updated: Feb 14, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Midface alterations in childhood as pathogenesis of obstructive sleep apnea syndrome]
José de Jesús Rangel Chávez1, Cynthia Espinosa Martínez1, Aldo Uzziel Medina Serpa2
1Hospital de Especialidades Médicas de la Salud, San Luis Potosí, San Luis Potosí, México; Hospital Lomas de San Luis Internacional, San Luis Potosí, San Luis Potosí, México.
Abstract:
The onset of nasal breathing sets a genetically determined impulse to aerate the face cavities or paranasal sinuses, which in turn initiate its growth creating the useful trafficable space for air during the development of the midface. Considering the evidence that the upper airway obstruction has a primary role in the pathogenesis of respiratory sleep disorders, any condition that causes a permanent difficulty to the nasal airflow during breathing will cause hypo-development of the required amplitude in this airway, reducing the growth stimulation of the sinus cavities and altering the development of the midface as a whole.
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