Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pressure Relationships in Thoracic Cavity01:24

Pressure Relationships in Thoracic Cavity

7.0K
Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs...
7.0K
Thoracic Aorta01:15

Thoracic Aorta

1.9K
The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
1.9K
The Thoracic Cage: Sternum01:17

The Thoracic Cage: Sternum

8.5K
The thoracic or rib cage forms the body's thorax (chest) portion. Its primary function in the body is to protect vital organs in the thoracic cavity, such as the heart and the lungs. It consists of 12 pairs of ribs with their costal cartilages and the sternum. The ribs are anchored posteriorly to the 12 thoracic vertebrae (T1-T12).
The sternum is the elongated bony structure on the anterior side of the thoracic cage. It consists of three parts: the manubrium, the body, and the xiphoid...
8.5K
The Thoracic Cage: Ribs01:20

The Thoracic Cage: Ribs

9.3K
Ribs are curved, flattened bones forming the thoracic cavity wall with the thoracic muscles. There are 12 pairs of thoracic ribs. The posterior ends of all the ribs articulate with the T1–T12 thoracic vertebrae. In contrast,the anterior ends of most ribs attach to the sternum via their costal cartilages.
Parts of a Typical Rib
A typical rib has a head, neck, and body. The posterior end of the rib is called the head, followed by a narrow neck. The head articulates primarily with the costal...
9.3K
Vapor Pressure02:34

Vapor Pressure

41.1K
When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules move randomly about, they will occasionally collide with the surface of the condensed phase, and in some cases, these collisions will result in the molecules re-entering the condensed phase. The change from the gas phase to the liquid is called condensation. When the rate of condensation becomes equal to the rate of vaporization, neither the amount of the liquid nor the amount of the vapor...
41.1K
Definition and Measurement of Pressure: Atmospheric Pressure, Barometer, and Manometer02:57

Definition and Measurement of Pressure: Atmospheric Pressure, Barometer, and Manometer

43.8K
Gas pressure is caused by force exerted by gas molecules colliding with the surfaces of objects. Although the force of each collision is very small, any surface of an appreciable area experiences a large number of collisions in a short time, which can result in high pressure.
43.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global Initiative for Asthma Updates for Diagnosing Asthma in Adults.

JAMA network open·2026
Same author

Generative artificial intelligence-driven chatbots and medical misinformation: an accuracy, referencing and readability audit.

BMJ open·2026
Same author

What's (Not) in Your Supplement? An Energy and Macronutrient Analysis of Commercially Available Carbohydrate Gels.

International journal of sport nutrition and exercise metabolism·2024
Same author

The repeatability of a cycling exercise-heat stress test in a male population.

Journal of thermal biology·2024
Same author

Decoding Ultramarathon: Muscle Damage as the Main Impediment to Performance.

Sports medicine (Auckland, N.Z.)·2024
Same author

Asthma diagnosis: a comparison of established diagnostic guidelines in adults with respiratory symptoms.

EClinicalMedicine·2024

Related Experiment Video

Updated: Feb 14, 2026

A Novel Non-invasive Method for the Detection of Elevated Intra-compartmental Pressures of the Leg
04:34

A Novel Non-invasive Method for the Detection of Elevated Intra-compartmental Pressures of the Leg

Published on: May 31, 2019

9.7K

Effect of spirometry on intra-thoracic pressures.

Nicholas B Tiller1,2, Andrew J Simpson3,4

  • 1Academy of Sport and Physical Activity, Sheffield Hallam University, Sheffield, S10 2BP, UK. n.tiller@shu.ac.uk.

BMC Research Notes
|February 10, 2018
PubMed
Summary

Spirometry generates high intra-thoracic pressures, especially during forced expiration, potentially harming vulnerable patients. These pressures during spirometry can approach maximal expiratory values, highlighting safety concerns.

Keywords:
Balloon catheterLung functionPressurePulmonary functionSpirometryintra-thoracic pressure

More Related Videos

Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome
06:57

Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome

Published on: September 13, 2020

4.2K
Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy
05:03

Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy

Published on: April 17, 2020

5.9K

Related Experiment Videos

Last Updated: Feb 14, 2026

A Novel Non-invasive Method for the Detection of Elevated Intra-compartmental Pressures of the Leg
04:34

A Novel Non-invasive Method for the Detection of Elevated Intra-compartmental Pressures of the Leg

Published on: May 31, 2019

9.7K
Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome
06:57

Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome

Published on: September 13, 2020

4.2K
Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy
05:03

Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy

Published on: April 17, 2020

5.9K

Area of Science:

  • Pulmonary Physiology
  • Respiratory Medicine

Background:

  • Spirometry is contraindicated for certain patients due to high intrathoracic pressures during maneuvers.
  • The precise pressure dynamics during spirometry have not been well-documented.

Purpose of the Study:

  • To quantify the intra-thoracic pressure response during spirometry.
  • To assess the potential risks associated with spirometry in vulnerable populations.

Main Methods:

  • Eight healthy male participants performed spirometry.
  • Oesophageal pressure was continuously monitored using a catheter-tipped balloon transducer.

Main Results:

  • Peak inspiratory oesophageal pressure reached -47 ± 9 cmH2O (37% of maximal inspiratory pressure).
  • Peak expiratory oesophageal pressure reached 102 ± 34 cmH2O (75% of maximal expiratory pressure).

Conclusions:

  • Spirometry induces significant intrathoracic pressures, particularly during forced expiration.
  • These high pressures may explain the contraindication of spirometry for patients with certain conditions.