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Multifocal Spinal Cord Nephroblastoma in a Dog.
L C Henker1, R M Bianchi1, T P Vargas1
1Department of Veterinary Pathology, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090 Pr. 42505, Porto Alegre, Brazil.
Journal of Comparative Pathology
|February 10, 2018
Summary
A rare multifocal spinal cord nephroblastoma was diagnosed in a dog. This canine tumor affected multiple spinal cord regions, presenting a unique diagnostic challenge.
Area of Science:
- Veterinary Pathology
- Canine Neurology
- Neoplasia
Background:
- Spinal cord tumors in dogs can cause progressive neurological deficits.
- Nephroblastomas are rare in dogs, typically affecting younger animals.
Observation:
- A 1-year-old pit bull terrier presented with hindlimb lameness and proprioceptive deficits, progressing to tetraparesis.
- Necropsy revealed multiple intradural, extramedullary masses within the spinal cord.
Findings:
- Histopathology showed a nephroblastoma composed of epithelial, stromal, and blastemal cells.
- Immunohistochemistry confirmed cell types with vimentin, cytokeratin, and S100 positivity.
- This case represents the first report of multifocal spinal cord nephroblastoma involving multiple spinal regions.
Implications:
- Highlights the importance of considering rare spinal cord tumors in canine neurological cases.
- Provides a detailed pathological description of a unique canine nephroblastoma presentation.
- Contributes to the understanding of spinal neoplasia in veterinary medicine.
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