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Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
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STN DBS for Advanced Parkinson Disease Simultaneously Alleviates Cluster Headache
Antti Huotarinen1, Martin Reich2, Jens Volkmann2
1Department of Neurosurgery, Helsinki University Hospital, and Division of Neurosurgery, Clinical Neurosciences, University of Helsinki, Helsinki, Finland.
Case Reports in Neurology
|February 10, 2018
Summary
Deep brain stimulation of the subthalamic nucleus (STN DBS) effectively treated Parkinson disease and cluster headache in a patient. STN DBS alleviated both conditions, allowing for withdrawal of cluster headache medication.
Area of Science:
- Neurology
- Neurosurgery
Background:
- Subthalamic nucleus deep brain stimulation (STN DBS) is a standard treatment for advanced Parkinson disease (PD).
- Posterior hypothalamic deep brain stimulation (DBS) for cluster headache (CH) is still under investigation.
Observation:
- A patient with both advanced PD and CH was treated with bilateral STN DBS due to L-dopa side effects.
- The patient received medical management for both conditions prior to DBS.
Findings:
- STN DBS successfully reduced symptoms of both PD and CH.
- The patient's CH treatment was discontinued following successful STN DBS.
- Symptomatic relief for CH persisted during follow-up, despite PD progression.
Implications:
- STN DBS may offer a dual therapeutic benefit for patients with comorbid PD and CH.
- The shared neuroanatomical pathways between the subthalamic nucleus and hypothalamus might explain the concurrent symptom relief.
- Further research into the autonomic effects of STN DBS could elucidate its broader therapeutic potential.
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