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A Protocol to Infect Caenorhabditis elegans with Salmonella typhimurium
Published on: June 26, 2014
Salmonella typhimurium: a rare cause of mesh-related infection
Ankur Sidhu1,2, Su Kah Goh1,2, Eunice Lee1,2
1Hepato-pancreato-biliary and Transplantation Unit, Austin Health, The University of Melbourne, VIC 3084, Australia.
Abstract:
The use of mesh in the management of abdominal wall hernias has significantly reduced the incidences of hernia recurrences. The placement of synthetic meshes to reinforce the abdominal wall is not without caveats. Synthetic meshes are associated with a risk of infection. Common causative microorganisms for mesh-related infection range from a diversity of gram positive, gram negative and anaerobic bacteria. However, non-typhoidal Salmonella spp. mesh-related infection remains poorly described in the literature. In this case, we report the management of an immunocompromised patient who developed Salmonella typhimurium mesh-related infection that was complicated by abscess formation.
Insights
Synthetic mesh use for abdominal wall hernias reduces recurrence but carries infection risks. This case highlights a rare Salmonella typhimurium mesh infection in an immunocompromised patient, complicated by abscess.
Area of Science:
- Infectious Diseases
- Surgical Innovation
- Microbiology
Background:
- Synthetic mesh significantly lowers hernia recurrence rates in abdominal wall repair.
- However, synthetic meshes present a risk of surgical site infections.
- Common pathogens include gram-positive, gram-negative, and anaerobic bacteria.
Observation:
- Non-typhoidal Salmonella spp. mesh infections are infrequently documented.
- This case involves an immunocompromised individual with a Salmonella typhimurium mesh infection.
- The infection led to the formation of a complicated abscess.
Findings:
- Successful management of a rare Salmonella typhimurium mesh infection in an immunocompromised patient.
- Demonstrates the challenges of treating deep-seated infections with synthetic materials.
- Highlights the importance of considering unusual pathogens in mesh infections.
Implications:
- Clinicians should consider Salmonella spp. in the differential diagnosis of mesh infections, especially in immunocompromised hosts.
- Further research is needed to understand the pathogenesis and optimal treatment of Salmonella-related mesh infections.
- This case underscores the need for vigilance regarding potential complications associated with synthetic mesh use in hernia repair.
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