Related Experiment Videos
A comparative study of the metabolic effects of injectable and oral contraceptives
Contraception
|April 1, 1986
Abstract:
The metabolic effects of an injectable contraceptive, Depo-provera (medroxyprogesterone acetate), an oral contraceptive pill containing 50 micrograms ethinyl estradiol and 500 micrograms norgestrel and a control group (not on contraceptives) were compared in 3 groups, each comprising 32 women. The subjects were matched for race, age and parity. Mean duration of treatment was 41.7 +/- 18.3 months for Depo-provera and 59.6 +/- 29.0 months for the pill group. Glucose tolerance was impaired in both treatment groups. The combination pill showed more changes in both glucose tolerance and insulin response. Lipid levels remained unchanged in both treatment groups.
Keywords:
Age FactorsAnthropometryAsiaBiologyBody WeightCarbohydrate Metabolic EffectsComparative StudiesContraceptionContraceptive AgentsContraceptive Agents, Estrogen--administraction and dosageContraceptive Agents, FemaleContraceptive Agents, Progestin--administraction and dosageContraceptive Agents--administraction and dosageContraceptive Methods--side effectsDepo-provera--administraction and dosageDeveloping CountriesDiseasesEndocrine SystemEthinyl Estradiol--administraction and dosageEvaluationExaminations And DiagnosesFamily PlanningFertility MeasurementsGlucose Tolerance Test--analysisHormonesInjectables--side effectsLaboratory Examinations And DiagnosesLaboratory ProceduresLipid Metabolic EffectsLipidsMeasurementMedroxyprogesterone AcetateMetabolic EffectsNorgestrel--administraction and dosageParityPhysiologyPopulation CharacteristicsReproductive Control AgentsResearch MethodologySingaporeSoutheastern AsiaStudies