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The superior view of the cranium shows the frontal and paired parietal bones.
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The subclavian artery transitions into the axillary artery as it exits the chest and enters the axillary region. This artery is critical for supplying blood to the shoulder area, including the head of the humerus, through the humeral circumflex arteries. As the vessel continues into the upper arm or brachium, it becomes the brachial artery. This artery plays a key role in vascularizing the brachial region and bifurcates at the elbow into several branches. These branches include the deep...
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Related Experiment Video

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Posterior Ciliary Artery Occlusion.

Sohan Singh Hayreh1

  • 1Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, Iowa.

Ophthalmology. Retina
|February 10, 2018
PubMed
Summary

Old, atherosclerotic monkeys experienced similar ischemic damage to the eye after posterior ciliary artery occlusion as young monkeys. This contrasts with central retinal artery occlusion, where young monkeys showed more severe damage.

Area of Science:

  • Ophthalmology
  • Vascular Biology
  • Comparative Pathology

Background:

  • Posterior ciliary artery (PCA) occlusion can cause significant ocular damage.
  • Age and comorbidities like atherosclerosis and hypertension may influence ischemic injury severity.

Purpose of the Study:

  • To compare ischemic damage severity in young, healthy monkeys versus old, atherosclerotic, hypertensive monkeys following PCA occlusion.

Main Methods:

  • Experimental occlusion of all PCAs in both young (n=7) and old (n=8) rhesus monkeys.
  • Evaluation using ophthalmoscopy, fundus photography, and fluorescein angiography before and after occlusion.

Main Results:

  • Both groups developed acute ischemic infarction of the choroid, retina, and optic nerve head within 24 hours.

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  • No statistically significant difference in acute ischemic lesion severity was observed between the groups.
  • Long-term follow-up showed similar resolution of lesions, choroidal vessel unmasking, and optic atrophy in both groups.

    • Conclusions:

    • PCA occlusion severity is comparable between young and old, comorbid monkeys.
    • This finding differs from central retinal artery occlusion studies, where young animals showed greater damage.