Related Experiment Video
Updated: Feb 14, 2026
05:52
Novel Mini-open Transforaminal Lumbar Interbody Fusion
Published on: June 6, 2025
764
Reoperation within 2 years after lumbar interbody fusion: a multicenter study
Kazuyoshi Kobayashi1, Kei Ando1, Fumihiko Kato2
1Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65, Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8560, Japan.
Summary
Reoperation after lumbar fusion surgery (PLIF/TLIF) is uncommon but linked to factors like the number of fused levels. Fusing two or more levels significantly increases the risk of needing another surgery within two years.
Area of Science:
- Spine surgery
- Orthopedics
- Neurosurgery
Background:
- Posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) are common spinal procedures.
- Complications following these surgeries can necessitate reoperation, impacting patient outcomes.
Purpose of the Study:
- To identify significant risk factors associated with reoperation within two years after PLIF/TLIF procedures.
- To analyze the causes and predictors of early reoperation in lumbar fusion patients.
Main Methods:
- Retrospective analysis of a prospective multicenter database including 1363 patients who underwent PLIF/TLIF.
- Comparison of comorbidities, perioperative factors, and operative details between patients with and without reoperation.
- Multivariate logistic regression analysis to determine independent risk factors for reoperation.
Main Results:
- A total of 38 reoperations (2.8%) occurred within two years post-PLIF/TLIF.
- Common reasons for reoperation included adjacent segment degeneration, surgical site infection, and screw misplacement.
- Fusion of two or more levels (HR 2.19) was identified as a significant risk factor for reoperation.
Conclusions:
- Surgical invasiveness, indicated by the number of fused levels, operation time, estimated blood loss, and dural tear, is associated with increased reoperation rates.
- Performing fusion across two or more levels is a strong predictor of reoperation within two years following initial PLIF/TLIF surgery.
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