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Updated: Feb 14, 2026

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Published on: August 6, 2012
Highly efficient direct oxygen electro-reduction by partially unfolded laccases immobilized on waste-derived
Daily Rodríguez-Padrón1, Alain R Puente-Santiago, Alvaro Caballero
1Departamento de Química Orgánica, Grupo FQM-383, Universidad de Córdoba, Campus de Rabanales, Edificio Marie Curie (C-3), Ctra Nnal IV-A, Km 396, E14014, Córdoba, Spain. q62alsor@uco.es apuentesantiago@gmail.com.
Abstract:
A biocatalytic system based on laccase functionalized waste-derived iron oxide nanoparticles (LAC-DA-Fe2O3) was designed by a mechanochemical approach and employed in the electrocatalytic reduction of oxygen. Full characterization of the obtained bioconjugates revealed that the protein adopted a partially unfolded state. The mentioned configuration, together with the geometry coordination changes along the T1 center can be further related to a high bioelectrocatalytic response. A current density up to 2.9 mA cm-2 has been achieved, which is among the highest values reported in literature for laccase functionalized nanomaterials.
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