Related Experiment Video
Updated: Feb 14, 2026
05:50
Contrast Enhanced Vessel Imaging using MicroCT
Published on: January 27, 2011
13.2K
Improved Contrast-Enhanced Ultrasound Imaging With Multiplane-Wave Imaging
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
|February 10, 2018
Summary
This study introduces a new Multiplane-Wave Contrast-Enhanced Ultrasound (MW-CEUS) method. It enhances signal-to-noise ratio for deeper imaging without increasing mechanical index, improving ultrasound clinical applications.
Area of Science:
- Medical Imaging
- Ultrasound Technology
- Biomedical Engineering
Background:
- Contrast-enhanced ultrasound (CEUS) uses microbubbles for enhanced imaging.
- Deep imaging in CEUS suffers from low signal-to-noise ratio (SNR) at low mechanical index (MI).
- Low MI is necessary to prevent microbubble disruption, especially at off-resonance frequencies.
Purpose of the Study:
- To improve CEUS imaging SNR in deeper regions.
- To achieve better SNR without increasing MI or reducing frame rate.
- To adapt CEUS for challenging clinical applications like deep abdominal or cardiac imaging.
Main Methods:
- Combined CEUS sequences with multiplane-wave (MW) compounding.
- Emitted multiple Hadamard-coded CEUS pulses per transmission event.
- Applied fundamental bandpass filtering, Hadamard decoding, and signal recombination to cancel linear tissue responses.
Main Results:
- Significantly improved contrast-to-tissue ratio and SNR in CEUS imaging.
- Preserved image resolution compared to classic CEUS.
- Similar microbubble disruption ratio and motion artifacts as classic CEUS.
Conclusions:
- The MW-CEUS method enhances SNR and contrast for deep imaging applications.
- This technique facilitates broader clinical use of CEUS, particularly for deep organs.
- The MW-CEUS sequence is adaptable to other transmission coding formats.
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