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Relationship Between Xanthelasma Palpebrarum and Hyperlipidemia
Annals of Plastic Surgery
|February 10, 2018
Summary
Xanthelasma lesions are frequently linked to dyslipidemia. Patients diagnosed with xanthelasma should undergo lipid profiling and manage lipid abnormalities through diet and medication.
Area of Science:
- Dermatology
- Ophthalmology
- Cardiology
Background:
- Xanthelasma palpebrarum is a common periorbital skin condition.
- A strong association exists between xanthelasma and dyslipidemia.
- Various treatment modalities yield comparable outcomes.
Purpose of the Study:
- To investigate the association between xanthelasma and dyslipidemia.
- To analyze recurrence rates and treatment effectiveness for xanthelasma.
Main Methods:
- Retrospective chart review of 113 patients with xanthelasma.
- Analysis of surgical and non-surgical treatment data from 1994 to 2012.
- Evaluation of serum lipid levels, comorbidities, and recurrence rates using SAS 9.4.
Main Results:
- 50% of patients with available lipid data had dyslipidemia, exceeding general population rates.
- The overall recurrence rate for xanthelasma was 17.5%.
- No significant difference in recurrence rates was observed across different treatment methods.
Conclusions:
- Xanthelasma is significantly associated with dyslipidemia.
- Recommend lipid profile screening for xanthelasma patients.
- Emphasize diet control and lipid-lowering therapy for associated lipid abnormalities.
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