Related Experiment Video
Updated: Feb 14, 2026

Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique
Published on: September 23, 2022
Influenza Vaccination Coverage in Children With Neurologic Disorders and Their Siblings, July 2006 to June 2014
Fiona P Havers1, Alicia M Fry1, Georgina Peacock2
1From the Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention.
Insights
Children with neurologic disorders face high flu risks. While influenza vaccination coverage increased, it remained suboptimal, highlighting a need for improved public health strategies for this vulnerable pediatric population.
Area of Science:
- Pediatric Neurology
- Infectious Disease Epidemiology
- Public Health
Background:
- Children with neurologic disorders (ND) are recognized as a high-risk group for severe influenza and its complications.
- Influenza vaccination is a critical preventive measure for high-risk pediatric populations.
Purpose of the Study:
- To analyze influenza vaccination coverage trends among children with neurologic disorders and their siblings.
- To assess the adequacy of vaccination coverage in this specific pediatric cohort.
Main Methods:
- A retrospective cohort study was conducted using a commercial insurance claims database.
- Data from 184,460 children aged 1-17 years with neurologic disorders and 204,966 siblings were analyzed from July 2006 to June 2014.
Main Results:
- Influenza vaccination coverage among children with neurologic disorders increased from 22.4% in 2006-2007 to 42.3% in 2013-2014.
- Despite the increase, vaccination coverage remained suboptimal throughout the study period.
- A lower proportion of siblings of children with neurologic disorders received influenza vaccination compared to their affected counterparts.
Conclusions:
- Influenza vaccination rates for children with neurologic disorders show an upward trend but have not reached optimal levels.
- Targeted interventions are necessary to improve influenza vaccine uptake in children with neurologic disorders and their families.
- Further research is needed to understand barriers to vaccination and to implement effective strategies for this vulnerable population.
Abstract:
Children with neurologic disorders are at high risk for influenza-associated complications. We identified 184,460 children 1-17 years of age with neurologic disorders and 204,966 siblings in a commercial insurance claims database from July 2006 to June 2014. Among children with neurologic disorders, coverage increased from 22.4% in 2006-2007 to 42.3% in 2013-2014, but remained suboptimal. A lower proportion of siblings were vaccinated.
More Related Videos
Related Concept Videos
Vaccinations
Relationship with Other Adult Family Members and Siblings
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Intrinsically Disordered Proteins
Drug Dosing: Infants and Children
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

