Related Experiment Video
Updated: Feb 14, 2026

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
Published on: October 22, 2014
Carbohydrate antigen 125: a promising tool for risk stratification in heart diseases
Felipe Falcão1,2,3, Flávio R A de Oliveira2,3,4, Maria Cleide F C da Silva4
1Universidade de Pernambuco, Departamento de Medicina Interna, Garanhuns, Brazil.
Abstract:
All patients with heart diseases should undergo risk stratification to predict those who are at high risk for short- and long-term adverse outcomes. Carbohydrate antigen 125 (CA125) is a glycoprotein produced by mesothelium that has clinical role in ovarian cancer monitoring. However, as it is not specific for ovarian cells, CA125 could also be used in heart diseases to monitor congestion and inflammation. Pericarditis, atrial fibrillation, heart failure and coronary artery disease are some scenarios in which this biomarker was studied.CA125 identifies patients at high risk of rehospitalizations and death, in addition to being associated with hemodynamic data (ejection fraction and right atrial pressure). Hence, CA125 is a tool for risk stratification in heart diseases.
Related Concept Videos
What are Carbohydrates?
Chemistry of Carbohydrates
Chemistry of Carbohydrates
Carbohydrate Digestion
Rheumatic Heart Disease I: Introduction
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...

