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Updated: Feb 14, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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Published on: July 4, 2016

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Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2

Wang Zheng1, Ruiqi Cai2, Laura Hofmann3

  • 1National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, Hubei 430068, China; Membrane Protein Disease Research Group, Department of Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.

Cell Reports
|February 10, 2018
PubMed

Keywords:
PIP2TRPTRP domainelectrophysiologygatingintramolecular interactionpre-S1

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