Acromegalic arthropathy: a reversible rheumatic disease

Acromegalic arthropathy may be the initial manifestation of growth hormone over-production. The presence of an underlying endocrinopathy may go unrecognized for a long period of time because of the predominance of articular signs and symptoms. We describe 2 cases of acromegaly presenting with rheumatologic manifestations, the first resembling seronegative rheumatoid arthritis, the second, post traumatic low back syndrome. Unlike previous reports, both our cases showed resolution of musculoskeletal symptoms after pituitary surgery.