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Acromegalic arthropathy: a reversible rheumatic disease.
The Journal of Rheumatology
|June 1, 1986
Summary
Acromegaly, a condition of excess growth hormone, can initially present as joint pain mimicking arthritis. Pituitary surgery effectively resolved these musculoskeletal symptoms in two patients.
Area of Science:
- Endocrinology
- Rheumatology
- Neurosurgery
Background:
- Acromegaly, caused by excess growth hormone, often presents with musculoskeletal issues.
- Articular symptoms can mask the underlying endocrine disorder, delaying diagnosis.
Observation:
- Two cases of acromegaly with prominent rheumatologic manifestations are presented.
- The first case mimicked seronegative rheumatoid arthritis; the second resembled post-traumatic low back syndrome.
Findings:
- Musculoskeletal symptoms in both patients resolved following pituitary surgery.
- This suggests a direct link between growth hormone excess and the observed arthropathy.
Implications:
- Highlights the importance of considering acromegaly in patients with unexplained rheumatologic symptoms.
- Demonstrates the efficacy of surgical intervention for acromegaly-related musculoskeletal complaints.