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Cancer molecular markers: A guide to cancer detection and management
Meera Nair1, Sardul Singh Sandhu2, Anil Kumar Sharma3
1Stem Cell Technology Laboratory, Centre for Scientific Research & Development, People's University, Bhopal, M.P., 462037, India; Biological Science Department, Rani Durgavati University, Jabalpur, M.P., 482001, India.
Abstract:
Cancer is generally caused by the molecular alterations which lead to specific mutations. Advances in molecular biology have provided an impetus to the study of cancers with valuable prognostic and predictive significance. Over the hindsight various attempts have been undertaken by scientists worldwide, in the management of cancer; where, we have witnessed a number of molecular markers which allow the early detection of cancers and lead to a decrease in its mortality rate. Recent advances in oncology have led to the discovery of cancer markers that has allowed early detection and targeted therapy of tumors. In this context, current review provides a detail outlook on various molecular markers for diagnosis, prognosis and management of therapeutic response in cancer patients.
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