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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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The Evidence for Evolution02:55

The Evidence for Evolution

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Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
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Related Experiment Video

Updated: Feb 14, 2026

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
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Evidence-based clinical practice guidelines for inflammatory bowel disease.

Katsuyoshi Matsuoka1, Taku Kobayashi1, Fumiaki Ueno2,3

  • 1Guidelines Committee for Creating and Evaluating the ''Evidence-Based Clinical Practice Guidelines for Inflammatory Bowel Disease in Japan'', The Japanese Society of Gastroenterology (JSGE), 6F Shimbashi i-MARK Building, 2-6-2 Shimbashi, Minato-ku, Tokyo, 105-0004, Japan.

Journal of Gastroenterology
|February 12, 2018
PubMed
Summary

Updated clinical practice guidelines for inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn

Keywords:
ConsensusCrohn’s diseaseEvidenceGuidelinesInflammatory bowel diseaseUlcerative colitis

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Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease
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Area of Science:

  • Gastroenterology
  • Clinical Practice Guidelines
  • Evidence-Based Medicine

Background:

  • Inflammatory bowel disease (IBD) encompasses chronic conditions affecting the gastrointestinal tract and potentially other organs.
  • Advances in IBD pathogenesis, diagnostics, and therapeutics necessitate guideline updates.
  • Previous guidelines required revision due to new clinical knowledge.

Purpose of the Study:

  • To present an updated English version of evidence-based clinical practice guidelines for IBD.
  • To incorporate recent advancements in the diagnosis and treatment of ulcerative colitis (UC) and Crohn's disease (CD).

Main Methods:

  • Revision of existing Japanese guidelines for UC and CD, originally updated in 2016.
  • Selection of 59 clinical questions across 9 categories relevant to IBD management.
  • Literature search conducted using MEDLINE, Cochrane, and Igaku Chuo Zasshi databases.
  • Development of guidelines based on the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system.
  • Recommendations formulated through Delphi rounds.

Main Results:

  • Comprehensive guidelines addressing clinical features, diagnosis, and treatment of IBD.
  • Specific recommendations for the management of ulcerative colitis (UC) and Crohn's disease (CD).
  • Inclusion of sections on extraintestinal complications, cancer surveillance, and IBD in special situations.

Conclusions:

  • The updated guidelines provide evidence-based recommendations for IBD management.
  • This English version facilitates broader clinical application of the latest IBD treatment strategies.
  • The guidelines aim to improve patient care for individuals with inflammatory bowel disease.