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Updated: Feb 14, 2026

Cultivating a Three-dimensional Reconstructed Human Epidermis at a Large Scale
Published on: May 28, 2021
Nasal reconstruction with silicone using customised impression technique.
Sanath Shetty1, Fahad Mohammed1, Janavi Kamath1
1Department of Prosthodontics, Crown and Bridge, Yenepoya Dental College, Mangalore, Karnataka, India.
Facial defects from cancer require reconstructive surgery or prosthetics. This case study highlights successful nasal reconstruction using silicone prosthetics after adenoid cystic carcinoma removal.
Area of Science:
- Reconstructive surgery
- Biomaterials science
- Oncology
Background:
- Facial defects necessitate surgical or prosthetic interventions.
- Prosthetic rehabilitation is crucial when surgical options are limited.
- Acquired facial defects can stem from trauma, infections, or neoplasms.
Observation:
- A patient presented with an acquired nasal defect.
- The defect resulted from surgical treatment of adenoid cystic carcinoma.
- This condition required prosthetic rehabilitation.
Findings:
- Silicone was selected as the optimal material for prosthetic reconstruction.
- The silicone prosthesis effectively addressed the nasal defect.
- This approach provided a viable solution for the patient's condition.
Implications:
- Silicone prosthetics offer a reliable method for restoring facial anatomy.
- This case demonstrates the efficacy of prosthetic rehabilitation in complex oncological defects.
- Further research into biomaterials for facial prosthetics is warranted.
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