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Updated: Feb 14, 2026

Contrast Enhanced Vessel Imaging using MicroCT
Published on: January 27, 2011
Phantom-based study exploring the effects of different scatter correction approaches on the reconstructed images
Connor Puett1, Christina Inscoe2, Yueh Z Lee1,2,3
1University of North Carolina at Chapel Hill, UNC/NCSU Joint Department of Biomedical Engineering, Chapel Hill, North Carolina, United States.
Abstract:
Stationary digital breast tomosynthesis (sDBT) is an emerging technology in which the single rotating x-ray tube is replaced by a fixed array of multiple carbon nanotube-enabled sources, providing a higher spatial and temporal resolution. As such, sDBT offers a promising platform for contrast-enhanced (CE) imaging. However, given the minimal enhancement above background with standard operational tube settings and iodine dosing, CE breast imaging requires additional acquisition steps to isolate the iodine signal, using either temporal or dual energy subtraction (TS or DES) protocols. Also, correcting for factors that limit contrast is critical, and scatter and noise pose unique challenges during tomosynthesis. This phantom-based study of CE sDBT compared different postacquisition scatter correction approaches on the quality of the reconstructed image slices. Beam-pass collimation was used to sample scatter indirectly, from which an interpolated scatter map was obtained for each projection image. Scatter-corrected projections provided the information for reconstruction. Comparison between the application of different scatter maps demonstrated the significant effect that processing has on the contrast-to-noise ratio and feature detectability ([Formula: see text]) in the final displayed images and emphasized the critical importance of scatter correction during DES.
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