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Updated: Feb 14, 2026

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
H-scan analysis of thyroid lesions
Gary R Ge1, Rosa Laimes2, Joseph Pinto3
1University of Rochester Medical Center, School of Medicine and Dentistry, Rochester, New York, United States.
Abstract:
The H-scan analysis of ultrasound images is a matched-filter approach derived from analysis of scattering from incident pulses in the form of Gaussian-weighted Hermite polynomial functions. This framework is applied in a preliminary study of thyroid lesions to examine the H-scan outputs for three categories: normal thyroid, benign lesions, and cancerous lesions within a total group size of 46 patients. In addition, phantoms comprised of spherical scatterers are analyzed to establish independent reference values for comparison. The results demonstrate a small but significant difference in some measures of the H-scan channel outputs between the different groups.
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