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Updated: Feb 14, 2026

Single Molecule Fluorescence Energy Transfer Study of Ribosome Protein Synthesis
Published on: July 6, 2021
Synthesis of Alternating Donor-Acceptor Ladder-Type Molecules and Investigation of Their Multiple Charge-Transfer
Zhengxu Cai1, Na Zhang1, Mohammad A Awais1
1Department of Chemistry, The University of Chicago, 929 E 57th Street, Chicago, IL, 60637, USA.
Abstract:
We describe the synthesis as well as the optical and charge-transport properties of a series of donor-acceptor (D-A) ladder-type heteroacenes. These molecules are stable, soluble, and contain up to 24 fused rings. Structural analyses indicated that the backbones of S 10r and Se 10r are bent in single crystals. The three 10-ring heteroacenes were functionalized with thiol anchoring groups and used for single-molecular conductance measurements. The highest conductance was observed for molecular wires containing a benzoselenadiazole (BSD) moiety, which exhibits the narrowest band gap. Multiple charge-transport pathways were observed in molecular wires containing either benzothiadiazole (BTD) or BSD. The conductance is a complex function of both energy gap and orbital alignment.
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