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Updated: Feb 14, 2026

Influenza A Virus Studies in a Mouse Model of Infection
Published on: September 7, 2017
Human infection with avian influenza A(H7N2) virus-Virginia, 2002
Pauline Terebuh1, Akini Adija1, Lindsay Edwards1
1Centers for Disease Control and Prevention, Atlanta, GA, USA.
Background:
In March 2002, an outbreak of low-pathogenic avian influenza (LPAI) A(H7N2) was detected among commercial poultry operations in Virginia.
Methods:
We performed a serosurvey of 80 government workers involved in efforts to control the outbreak.
Results:
One study participant who assisted with disposal of infected birds tested positive for neutralizing antibodies to influenza A(H7N2) by microneutralization assay and H7-specific IgM antibodies by enzyme-linked immunosorbent assay (ELISA). The acute infection was temporally associated with an influenza-like illness that resolved without hospitalization.
Conclusion:
This study documents the earliest evidence of human infection with an H7 influenza virus of the North American lineage.
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