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Probing Ligand Structure-Activity Relationships in Pregnane X Receptor (PXR): Efavirenz and 8-Hydroxyefavirenz

Bhargavi Narayanan1, Julie M Lade2, Carley J S Heck2

  • 1Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Hunterian 709, Baltimore, MD, USA.

Chemmedchem
|February 13, 2018
PubMed

Keywords:
cytochrome P450drug metabolismligand bindingmolecular dockingnuclear receptors

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