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Effects of prophylactic anticholinergic medications to decrease extrapyramidal side effects in patients taking acute

Ryan S D'Souza1,2, Christopher Mercogliano1, Elizabeth Ojukwu3

  • 1Department of Medicine, Reading Health System, West Reading, Pennsylvania, USA.

Emergency Medicine Journal : EMJ
|February 13, 2018
PubMed
Summary

Prophylactic diphenhydramine effectively reduces extrapyramidal symptoms when given with bolus antiemetics for acute migraine. However, it increases sedation and is not beneficial with infused antiemetics, making infusion without prophylaxis the preferred strategy.

Keywords:
admission avoidanceclincial managementemergency care systememergency care systemsemergency departmentsheadachetreatment

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