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Engineering Antiviral Agents via Surface Plasmon Resonance
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Localized surface plasmon resonance based biosensing.

Andrea Csáki1, Ondrej Stranik1, Wolfgang Fritzsche1

  • 1a Department Nanobiophotonics , Leibniz Institute of Photonic Technology (IPHT) , Jena , Germany.

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|February 13, 2018
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Summary
This summary is machine-generated.

Localized surface plasmon resonance (LSPR) biosensors are rapidly advancing with novel transducers and signal strategies. Future developments aim for cost-efficient, robust point-of-care solutions and multiplexed clinical applications.

Keywords:
Localized surface plasmon resonancebiosensoroptical sensorplasmonic nanostructuressensitivity

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Area of Science:

  • Bioanalytical chemistry
  • Nanotechnology
  • Sensor technology

Background:

  • Localized surface plasmon resonance (LSPR) sensing is a rapidly developing field.
  • Novel plasmonic transducers and signal development concepts are emerging.
  • This review provides an overview of LSPR sensor advancements.

Purpose of the Study:

  • To review the development of LSPR-based bioanalytical sensors.
  • To focus on transducer types, optimal sensing concepts, and usability.
  • To critically assess the potential of these devices as innovative biosensors.

Main Methods:

  • Review of recent literature on LSPR sensor development.
  • Analysis of transducer preparation, dimensions, and material properties.
  • Evaluation of signal enhancement strategies and read-out principles.

Main Results:

  • Plasmonic sensors show high potential for future biosensing.
  • Cost-efficient production is achievable with bottom-up synthesized nanoparticles.
  • LSPR imaging (LSPRi) enables multiplexed, high-throughput sensing.

Conclusions:

  • Addressing stability, sensitivity, and cost are key for plasmonic sensor viability.
  • Optimal LSPR concepts are trending towards cost-efficient point-of-care solutions.
  • Multiplexed LSPR devices hold promise for clinical applications.