Targeting the bone marrow microenvironment in acute leukemia.

Christina Karantanou1, Parimala Sonika Godavarthy1, Daniela S Krause1

  • 1a Institute for Tumor Biology and Experimental Therapy , Georg-Speyer-Haus , Frankfurt am Main , Germany.

Leukemia & Lymphoma
|February 13, 2018
PubMed
Summary

Acute leukemia survival remains low, as current therapies often fail to eliminate leukemic stem cells (LSCs). Targeting the bone marrow microenvironment (BMM) offers a promising strategy to overcome treatment resistance and improve outcomes.

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