Related Experiment Video
Updated: Jul 27, 2026

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
Published on: June 20, 2014
[The heart in dermatomyositis and polymyositis ]
A study of patients with Dermatomyositis (DM) and Polymyositis (PM) found that 82% experienced cardiopulmonary complications. Non-invasive cardiac assessments revealed frequent abnormalities, highlighting the significant cardiac impact of these inflammatory myopathies.
Area of Science:
- Cardiology
- Rheumatology
- Internal Medicine
Context:
- Inflammatory myopathies, including Dermatomyositis (DM) and Polymyositis (PM), can affect multiple organ systems.
- Cardiac involvement is a recognized but often underdiagnosed complication in these conditions.
Purpose:
- To investigate the cardiological status of patients with DM and PM using non-invasive methods.
- To identify the prevalence and types of cardiopulmonary complications in this patient cohort.
Summary:
- Eleven consecutive patients (8 DM, 3 PM) underwent non-invasive cardiological evaluation.
- Eighty-two percent (9/11) exhibited cardiopulmonary complications.
- Common findings included abnormal electrocardiograms (ECG), cardiac enlargement (right atrial/ventricular hypertrophy, left ventricular hypertrophy), bundle branch blocks, and echocardiographic abnormalities such as right ventricular hypertrophy, mitral valve prolapse (MVP), and congestive cardiomyopathy.
Impact:
- This study underscores the high incidence of cardiopulmonary involvement in DM and PM patients.
- Findings emphasize the need for routine non-invasive cardiac screening in these individuals.
- Early detection and management of cardiac complications can potentially improve patient outcomes.
Related Concept Videos
Layers of the Heart Wall
The myocardium, the thickest layer, consists of cardiac muscle cells interconnected by intercalated discs and crisscrossing connective tissue fibers. These muscle fibers contract...
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis III: Medical Management
Rheumatic Heart Disease I: Introduction
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

