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Updated: Feb 14, 2026

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Expression and Purification of Virus-like Particles for Vaccination
Published on: June 2, 2016
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[Vaccines: benefits have been forgotten]
Elisabetta Franco1, Laura Zaratti1, Elisa Terracciano2
1Dipartimento Biomedicina e Prevenzione, Università degli Studi di Roma "Tor Vergata", Italia.
Summary
Vaccination has dramatically reduced infectious diseases, but declining vaccine coverage risks disease resurgence due to forgotten health risks. This paper examines vaccine-preventable disease epidemiology and reintroduction threats.
Area of Science:
- Public Health
- Epidemiology
- Immunization
Background:
- Vaccination has historically controlled severe infectious diseases.
- Current vaccine assessment often overlooks benefits, focusing on side effects.
- Societal memory of vaccine-preventable disease impact has diminished.
Purpose of the Study:
- To analyze the epidemiology of major vaccine-preventable diseases.
- To highlight the risks associated with declining vaccination rates.
- To underscore the importance of maintaining high vaccine coverage.
Main Methods:
- Review of epidemiological data for key vaccine-preventable diseases.
- Analysis of trends in vaccine coverage.
- Assessment of disease reintroduction risks based on coverage levels.
Main Results:
- Significant reduction or elimination of diseases due to vaccination.
- Decreasing vaccine coverage trends observed in various regions.
- Increased risk of pathogen re-emergence if coverage falls below critical thresholds.
Conclusions:
- The benefits of vaccination in preventing widespread disease are substantial.
- Loss of societal memory regarding disease severity fuels vaccine hesitancy.
- Maintaining high vaccination coverage is crucial to prevent the re-emergence of dangerous infectious diseases.
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