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Since the early 2000s, computer-mediated communication (CMC) has grown rapidly, playing a crucial role in self-development. A key distinction between CMC and real-life interactions is the lack of a physically present partner. This absence makes non-verbal cues such as facial expressions, body language, and paralinguistic signals unavailable in CMC platforms like email, instant messaging, or social media. The lack of these cues can create ambiguity and complicate how feedback is interpreted.The...
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Most chemical reactions in cells require enzymes—biological catalysts that speed up the reaction without being consumed or permanently changed. They reduce the activation energy needed to convert the reactants into products. Enzymes are proteins, that usually work by binding to a substrate—a reactant molecule that they act upon.
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Ipilimumab induced digital vasculitis.

Amrita Padda1, Elena Schiopu2, Justin Sovich3

  • 1Division of Rheumatology, Department of Internal Medicine, University of Michigan, Floor 3, Reception A, 1500 E Medical Center Drive, SPC 5342, Ann Arbor, MI, 48109, USA. rithydpu@gmail.com.

Journal for Immunotherapy of Cancer
|February 14, 2018
PubMed
Summary
This summary is machine-generated.

Immune checkpoint inhibitors (ICIs) can cause rare side effects like vasculitis. This case study details digital ischemia management in a melanoma patient treated with Ipilimumab, highlighting the need for prompt IRAE recognition.

Area of Science:

  • Oncology
  • Immunology
  • Dermatology

Background:

  • Immune checkpoint inhibitors (ICIs) represent a significant advancement in cancer therapy, particularly for metastatic melanoma.
Keywords:
Immune related adverse events (IRAEs)IpilimumabVasculitis

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