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The Spared Nerve Injury SNI Model of Induced Mechanical Allodynia in Mice
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Cold intolerance after nerve injury.

Christine B Novak1

  • 1Toronto Western Hospital Hand Program, University Health Network, Toronto, Ontario, Canada; Division of Plastic & Reconstructive Surgery, University of Toronto, Toronto, Ontario, Canada.

Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists
|February 14, 2018
PubMed
Summary
This summary is machine-generated.

Cold intolerance following nerve injury causes significant pain and disability. Effective management involves objective and subjective assessments, alongside adaptive strategies and warming interventions to reduce cold-induced symptoms.

Keywords:
Cold intoleranceCold sensitivityManagementNerve injuryPain

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Area of Science:

  • Neurology
  • Pain Management
  • Rehabilitation Medicine

Background:

  • Peripheral nerve injury can lead to severe cold intolerance.
  • Cold-induced symptoms significantly impact patient pain and disability.

Purpose of the Study:

  • To provide an overview of assessment and nonoperative management strategies.
  • To discuss objective and subjective evaluation methods for cold intolerance.
  • To outline therapeutic approaches for managing cold-induced symptoms.

Main Methods:

  • Comprehensive evaluation including objective measures (e.g., skin temperature).
  • Utilizing subjective tools to assess patient-reported outcomes and symptom impact.
  • Reviewing nonoperative management techniques.

Main Results:

  • Assessment requires both objective and subjective data.
  • Management is challenging but can be improved with multimodal approaches.

Conclusions:

  • Effective management of cold intolerance post-nerve injury requires a comprehensive approach.
  • Strategies include adaptive measures, warming, and desensitization programs.
  • Minimizing cold-induced pain and hyperresponses is achievable.