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Long-term liver disease in methylmalonic and propionic acidemias.

Apolline Imbard1, Nuria Garcia Segarra2, Marine Tardieu3

  • 1Biochemistry Laboratory, APHP, Robert Debré University Hospital, Paris, France; Paris Sud University, Chatenay Malabry, France.

Molecular Genetics and Metabolism
|February 14, 2018
PubMed
Summary

Methylmalonic acidemia (MMA) and propionic acidemia (PA) can cause long-term liver abnormalities, including fibrosis and cirrhosis. Early liver function evaluation is crucial for these organic aciduria patients.

Keywords:
Alpha-fetoproteinHepatomegalyLiver diseaseLiver fibrosisMMAOXPHOS deficiencyOrganic acidemiasPA

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