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Updated: Feb 14, 2026
Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Evaluation of changes in left ventricular structure and function in hypertensive patients with coronary artery
Yanhong Meng1, Ling Zong2, Ziteng Zhang2
1Department of Ultrasound, The Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China.
Insights
Percutaneous coronary intervention (PCI) improved left ventricular function and synchrony in hypertensive patients with coronary artery disease. Real-time 3D echocardiography effectively tracked these positive changes post-PCI.
Area of Science:
- Cardiology
- Medical Imaging
- Hypertension Research
Background:
- Hypertension and coronary artery disease (CAD) often coexist, impacting left ventricular (LV) function.
- Percutaneous coronary intervention (PCI) is a common treatment for CAD, but its effect on LV structure and function in hypertensive patients requires detailed evaluation.
Purpose of the Study:
- To assess changes in LV structure and function in hypertensive patients with CAD before and after PCI.
- To evaluate the utility of real-time three-dimensional echocardiography (RT3DE) in monitoring these changes.
Main Methods:
- A study involving 280 hypertensive patients with CAD undergoing PCI and 120 controls.
- RT3DE was used to analyze LV volumes, ejection fraction (EF), and systolic synchrony indices (e.g., Tmsv-16SD) before and at 3 and 9 months after PCI.
- All patients received standard medical therapy.
Main Results:
- No significant baseline differences in LV end-diastolic volume, LV end-systolic volume (LVESV), or EF between groups.
- Post-PCI, the PCI group showed significantly decreased LVESV and increased EF at 3 and 9 months (P<0.05).
- Systolic synchrony parameters (Tmsv-16SD, Tmsv-16Dif, etc.) significantly improved in the PCI group post-treatment (P<0.05).
Conclusions:
- PCI leads to significant improvements in LV systolic function and synchrony in hypertensive patients with CAD.
- RT3DE is an accurate and real-time tool for evaluating prognostic parameters in these patients post-PCI.
Abstract:
We aimed to evaluate the changes in left ventricular structure and function in hypertensive patients with coronary artery disease before and after percutaneous coronary intervention (PCI) using real-time three-dimensional echocardiography. Two hundred and eighty hypertensive patients with coronary artery disease undergoing PCI and 120 cases who did not receive PCI in our hospital were selected as the subjects of our study. All patients were administered with routine antiplatelet, anticoagulant, lipid-lowering, antihypertensive, dilating coronary artery and other medications. The left ventricular systolic function and systolic synchrony index changes before and after subjects were treated by PCI were analyzed using three-dimensional echocardiography. At 2 days before surgery, there were no significant differences in the left ventricular end-diastolic volume, left ventricular end-systolic volume (LVESV) and ejection fraction (EF) between the two patient groups (P>0.05). At 3 months and 9 months, the two key time points after PCI, the LVESV level in the PCI group was distinctly decreased, while EF was significantly increased (P<0.05). In addition, before treatment, there were no significant differences in the parameters of time from the corresponding segment of the myocardium to the minimal systolic volume in two patient groups, such as Tmsv-16SD, Tmsv-16Dif, Tmsv-12SD, Tmsv-12Dif, Tmsv-6SD and Tmsv-6Dif (P>0.05); however, the parameters of time from the corresponding segment of the myocardium to the minimal systolic volume in patients in the PCI group were significantly reduced at 3 and 9 months after surgery (P<0.05). Three-dimensional echocardiography can evaluate the critical parameters in the prognosis of hypertensive patients with coronary artery disease after PCI accurately and in real-time, which may play a significant role.
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