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Updated: Feb 14, 2026

Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
Gastric reflux: comparison between the gastroenterologist and the otorhinolaryngologist’s approach. Pragmatic
1Ospedale Policlinico San Martino, Genoa, Italy
Conclusions:
Gastroesophageal reflux (GER) is a normal physiological process that usually happens after eating in healthy infants, children, young people and adults. In contrast, gastroesophageal reflux disease (GERD) occurs when the effect of GER leads to symptoms severe enough to merit medical treatment. In clinical practice, it is difficult to differentiate between GER and GERD, and health professionals and families use the terms interchangeably alike. There is no simple, reliable and accurate diagnostic test to confirm whether the condition is GER or GERD, and this in turn affects research and clinical decisions (1-6). Furthermore, the term GERD covers a number of specific conditions that have different effects and present in different ways. This makes it difficult to identify the person who genuinely has GERD, and to estimate the real prevalence and burden of the problem.
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