Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypoxic cor pulmonale: a review.

P Bardsley, R Evely, P Howard

    Herz
    |June 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Hypoxic cor pulmonale, often caused by chronic bronchitis and emphysema, involves edema formation not solely due to heart failure. Treatment focuses on controlled oxygen therapy and managing underlying respiratory conditions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A pilot monitoring strategy for post-partum disease in an Australian dairy herd.

    New Zealand veterinary journal·2021
    Same author

    'Warning: allergic to penicillin': association between penicillin allergy status in 2.3 million NHS general practice electronic health records, antibiotic prescribing and health outcomes.

    The Journal of antimicrobial chemotherapy·2019
    Same author

    A One Health investigation of Salmonella enterica serovar Wangata in north-eastern New South Wales, Australia, 2016-2017.

    Epidemiology and infection·2019
    Same author

    Man in Weightlessness.

    Journal of the Royal College of Physicians of London·2019
    Same author

    A national quality incentive scheme to reduce antibiotic overuse in hospitals: evaluation of perceptions and impact.

    The Journal of antimicrobial chemotherapy·2018
    Same author

    Human resources estimates and funding for antibiotic stewardship teams are urgently needed: authors' response.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2018
    Same journal

    [Heart and climate].

    Herz·2026
    Same journal

    Multidimensional psychosocial screening in routine cardiac care: preliminary findings from a cross-sectional survey.

    Herz·2026
    Same journal

    [Noise and the heart].

    Herz·2026
    Same journal

    [The cardiovascular exposome: areas of action for prevention and practical cardiology].

    Herz·2026
    Same journal

    Relationship between HAVOC score and new-onset atrial fibrillation in patients with ST elevation myocardial infarction.

    Herz·2026
    Same journal

    Interventional treatment of atrioventricular valves.

    Herz·2026
    See all related articles

    Area of Science:

    • Cardiology
    • Pulmonology
    • Nephrology

    Background:

    • Hypoxic cor pulmonale commonly stems from chronic bronchitis and emphysema.
    • Edema in these patients, even with arterial pO2 above 60 mm Hg, is an unfavorable prognostic indicator and not solely indicative of cardiac failure.
    • Edema formation is linked to salt and water retention or redistribution, influenced by hypercapnia, acidosis, and hormonal systems.

    Purpose of the Study:

    • To elucidate the mechanisms of edema formation in hypoxic cor pulmonale.
    • To discuss the prognostic significance of edema in this condition.
    • To outline current treatment strategies for acute exacerbations and chronic management.

    Main Methods:

    • Review of existing literature on hypoxic cor pulmonale, edema formation, and treatment modalities.

    Related Experiment Videos

  • Analysis of physiological mechanisms including renal function, hormonal influences (renin-angiotensin-aldosterone system, ADH), and sleep-related respiratory disturbances.
  • Evaluation of pharmacological and non-pharmacological treatment options.

    • Main Results:

    • Edema formation in hypoxic cor pulmonale is multifactorial, involving renal salt/water retention and extracellular fluid shifts, exacerbated by hypercapnia, acidosis, and hormonal activation.
    • Nocturnal hypoventilation, hypoxia during sleep, and sleep apnea can worsen cor pulmonale and respiratory insufficiency.
    • Secondary polycythemia is promoted by nocturnal hypoxia, smoking, and reduced renal oxygen tension.

    Conclusions:

    • Edema in hypoxic cor pulmonale is a complex issue not solely dependent on right or left ventricular failure.
    • Effective management includes addressing underlying respiratory diseases, controlled oxygen therapy for hypoxemia, and judicious use of diuretics and bronchodilators.
    • Antibiotics for infections, and potentially corticosteroids, are crucial in managing acute exacerbations.