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The Follow-Up Role of the Vestibular Evoked Myogenic Potential Test in Meniere's Disease

Nasrin Yazdani1, Farzaneh Nejadian1, Nima Rezazadeh2

  • 1Department of Otorhinolaryngology, Head and Neck Surgery, Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Acta Medica Iranica
|February 14, 2018
PubMed

Insights

The cervical vestibular evoked myogenic potential test is often unrecordable in Meniere's disease patients and doesn't change after intratympanic steroid injections, limiting its use for monitoring treatment response.

Area of Science:

  • Otolaryngology
  • Neuroscience
  • Vestibular System

Background:

  • Meniere's disease is a disorder of the inner ear.
  • Intratympanic steroid injections are used to treat Meniere's disease.
  • The diagnostic utility of cervical vestibular evoked myogenic potential (cVEMP) in Meniere's disease is debated, and its role in monitoring treatment response is unclear.

Purpose of the Study:

  • To evaluate the role of the cervical vestibular evoked myogenic potential (cVEMP) test in monitoring patients with Meniere's disease after intratympanic steroid injections.

Main Methods:

  • A prospective study included 31 adult patients with unilateral Meniere's disease refractory to medical treatment.
  • Patients received three intratympanic dexamethasone injections at weekly intervals.
  • The cVEMP test was performed before and four weeks after the last injection, with a one-year follow-up.

Main Results:

  • cVEMP was unrecordable in 83.9% of Meniere's disease patients.
  • Abnormal cVEMP results were found in 5 patients (16.1%), including the unaffected ear in 32.3% of cases.
  • Despite clinical symptom improvement post-treatment, cVEMP results remained unchanged.

Conclusions:

  • The cVEMP test is frequently unrecordable in Meniere's disease patients, unlike in healthy individuals.
  • cVEMP results do not change in the early phase after intratympanic steroid treatment.
  • The cVEMP test is not a suitable tool for follow-up or evaluating treatment response in Meniere's disease patients undergoing intratympanic steroid injections.
Keywords:
DexamethasoneFollow upIntratympanic injectionMeniere’s diseasecVEMP test

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