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Left axis deviation (LAD) in children is uncommon. Further cardiac workup is recommended if LAD is accompanied by ECG chamber enlargement, a QRS axis ≤-42°, or abnormal physical exam findings.

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Area of Science:

  • Pediatric Cardiology
  • Electrocardiography
  • Diagnostic Imaging

Background:

  • Left axis deviation (LAD) on electrocardiogram (ECG) is rare in children.
  • LAD can be associated with underlying heart disease (HD).
  • Optimal diagnostic strategies for asymptomatic children with LAD are unclear.

Purpose of the Study:

  • To identify predictors of heart disease in children with LAD.
  • To stratify risk for further cardiovascular investigation in pediatric patients with LAD.

Main Methods:

  • Retrospective chart review of patients aged 1-17 years with LAD (QRS axis 0 to -90).
  • Exclusion of patients with pre-existing heart disease.
  • Analysis of echocardiogram findings and clinical data.

Main Results:

  • 296 pediatric patients with LAD were identified.
  • 15% of patients who underwent echocardiography had heart disease.
  • Patients with HD were more likely to have a QRS axis ≤-42°, ECG chamber enlargement/hypertrophy, and abnormal cardiac exam findings.

Conclusions:

  • Isolated LAD in asymptomatic children may not require further investigation.
  • Echocardiography is indicated for LAD in conjunction with ECG chamber enlargement, QRS axis ≤-42°, or abnormal physical exam findings.