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Related Concept Videos

Relationship with Other Adult Family Members and Siblings01:29

Relationship with Other Adult Family Members and Siblings

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Other adult family members and siblings play a crucial role in shaping children’s social and emotional development. While parents or primary caregivers are often the central figures in early attachment and socialization, other adults in a child’s life, such as grandparents, aunts, and uncles, can significantly influence developmental outcomes. These influences depend on each adult’s personality and may help compensate when a primary caregiver is emotionally distant or...
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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Related Experiment Video

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A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia
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Consecutive siblings, each with two separate small bowel atresias.

Maria Chiara De Nardo1, Catherine Douch1, Louis Yee1

  • 1Neonatal Unit, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.

BMJ Case Reports
|February 14, 2018
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Familial intestinal atresia is rare. This report details two siblings with multiple intestinal atresia who underwent successful surgical repair, highlighting a unique familial case.

Keywords:
neonatal and paediatric intensive carepaediatric surgery

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Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Genetics

Background:

  • Multiple-level intestinal atresia is a rare congenital anomaly.
  • Familial occurrence of this condition is exceptionally uncommon in medical literature.

Observation:

  • The study presents a rare case of multiple intestinal atresia occurring in two consecutive siblings.
  • This familial aggregation of intestinal atresia is noteworthy due to its extreme rarity.

Findings:

  • Both siblings diagnosed with multiple intestinal atresia were successfully treated with surgical repair.
  • The successful surgical outcomes in this familial case provide valuable clinical data.

Implications:

  • This case underscores the importance of considering genetic factors in familial intestinal atresia.
  • Further research into the genetic basis of intestinal atresia may improve diagnostic and therapeutic strategies.