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Aging and calcium as an environmental factor.

Journal of Nutritional Science and Vitaminology

|December 1, 1985

Summary

Calcium deficiency poses risks to aging humans, potentially leading to bone loss and other chronic diseases. Addressing low calcium and vitamin D intake is crucial for maintaining health and preventing serious conditions.

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Area of Science:

Gerontology
Nutritional Science
Pathophysiology

Background:

Calcium deficiency is a significant health concern, particularly for aging mammals and humans.
Factors contributing to deficiency include poor intake, reduced sun exposure, and declining kidney function.

Purpose of the Study:

To explore the multifaceted consequences of calcium deficiency in aging populations.
To investigate the link between calcium imbalance and various chronic diseases.

Main Methods:

Review of physiological factors affecting calcium balance in aging.
Analysis of potential disease pathways linked to altered calcium distribution.

Main Results:

Calcium deficiency can lead to secondary hyperparathyroidism, bone loss, and osteoporosis.
Imbalances may cause calcium shifts to soft tissues and intracellular compartments, impacting cellular function.
Potential links to arteriosclerosis, hypertension, neurodegenerative diseases, diabetes, and immune deficiency were identified.

Conclusions:

Calcium deficiency has wide-ranging health implications beyond bone health.
Maintaining adequate calcium levels is vital for preventing age-related chronic diseases and supporting cellular function.

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