Related Experiment Video

Updated: Feb 14, 2026

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
08:45

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Published on: December 28, 2017

14.3K

Draft Genome Sequence of a Polymyxin B-Resistant Sequence Type 195 Clinical Isolate of Acinetobacter baumannii from

Bina Agarwal1,2, Niraj Agarwala3, Sarangapani Saikia2

  • 1Department of Biotechnology, Gauhati University, Jalukbari, Assam, India bina1986agarwal@gmail.com.

Genome Announcements
|February 14, 2018
PubMed

Insights

A polymyxin B-resistant Acinetobacter baumannii strain (ST195) was sequenced. This finding is crucial for understanding and combating drug-resistant bacterial infections in healthcare settings.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Acinetobacter baumannii is a significant global nosocomial pathogen.
  • Increasing antimicrobial resistance poses a major threat to public health.

Purpose of the Study:

  • To report the draft genome sequence of a polymyxin B-resistant Acinetobacter baumannii strain.
  • To characterize the genetic basis of resistance in a clinically relevant isolate.

Main Methods:

  • Whole-genome sequencing of Acinetobacter baumannii strain GU71.
  • Bioinformatic analysis of the draft genome sequence.
  • Identification of sequence type (ST195) and resistance determinants.

Main Results:

  • The draft genome sequence of Acinetobacter baumannii ST195 strain GU71 was obtained.
  • The strain was isolated from a tertiary care hospital in Guwahati, India.
  • The genome provides insights into the genetic makeup of this multidrug-resistant pathogen.

Conclusions:

  • The availability of this genome sequence aids in understanding the evolution and spread of drug-resistant Acinetobacter baumannii.
  • This data can inform strategies for infection control and treatment of Acinetobacter baumannii infections.

More Related Videos

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging09:29

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging

Published on: April 28, 2017

9.9K
Ultra-long Read Sequencing for Whole Genomic DNA Analysis10:34

Ultra-long Read Sequencing for Whole Genomic DNA Analysis

Published on: March 15, 2019

24.1K

Related Concept Videos

Cis-regulatory Sequences02:02

Cis-regulatory Sequences

Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
11.9K
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

4.2K
Sequences01:29

Sequences

Sequences are fundamental mathematical objects consisting of ordered lists of numbers that follow a specific rule or pattern. Sequences are critical in various mathematical concepts, including calculus, series, and number theory. They can model real-world phenomena such as population growth, financial investments, and physical processes like the diminishing height of a bouncing ball.Each number in a sequence is referred to as a term. Typically, the terms are denoted as a1, a2, a3,…, where...
308
Sanger Sequencing01:57

Sanger Sequencing

DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
775.2K
Arithmetic Sequences01:30

Arithmetic Sequences

An arithmetic sequence is a structured arrangement of numbers where each term is derived by adding a constant value, known as the common difference, to the previous term. This consistent pattern allows for the efficient computation of any term within the sequence as well as the cumulative sum of multiple terms. The formula for finding the nth term of an arithmetic sequence is:Here, aₙ represents the nth term of the sequence, a is the first term, d is the common difference, and n is the...
245
Geometric Sequences01:30

Geometric Sequences

In systems where values diminish by a constant proportion at each stage, the resulting sequence follows a geometric structure. Each new value in the sequence is obtained by applying a fixed multiplier to the preceding term. This regular, proportional decline type is often used to represent processes involving gradual loss, such as energy dissipation or reduction in amplitude over time.When analyzing the total effect of such a process across unlimited iterations, the series of values is referred...
296