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A case of lactate dehydrogenase (LDH)-IgG complex formation which causes low plasma LDH activity and an abnormal LDH
Japanese Journal of Medicine
|May 1, 1986
Abstract:
A case of an LDH-IgG complex formation which causes low plasma LDH activity and an abnormal LDH isozyme pattern was reported. A patient had pericarditis and myocardial hypertrophy of asymmetrical septal hypertrophy type. The same IgG was recognized in pericardial effusion. From a column chromatographic study, the molecular weight of LDH-IgG complex was estimated as being about 490,000. This complex was speculated as the IgG1-LDH2. The mechanism by which LDH-IgG is formed and the relationship between the complex itself and cardiac diseases remain unknown.