Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renal vascular hypertension. Surgery vs. dilation.

C E Grim, H Y Yune, J P Donohue

    Nephron
    |January 1, 1986
    PubMed
    Summary

    Renal artery stenosis treatments like surgery or angioplasty show varied success. Atherosclerotic disease often benefits, but fibrodysplastic disease carries risks, highlighting the importance of lesion etiology in blood pressure outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Usefulness of mean platelet volume as a marker for clinical outcomes after out-of-hospital cardiac arrest: a retrospective cohort study.

    Journal of thrombosis and haemostasis : JTH·2016
    Same author

    AGT and RH blood group polymorphisms affect blood pressure and lipids in Afro-Caribbeans.

    Journal of human hypertension·2004
    Same author

    Allelic variation in the promoter region of the LDL receptor gene: analysis of an African-specific variant in the FP2 cis-acting regulatory element.

    Molecular and cellular probes·2003
    Same author

    Omapatrilat versus lisinopril: efficacy and neurohormonal profile in salt-sensitive hypertensive patients.

    Hypertension (Dallas, Tex. : 1979)·2001
    Same author

    Predictors of target organ damage in hypertensive blacks and whites.

    Hypertension (Dallas, Tex. : 1979)·2001
    Same author

    Impact of diet on blood pressure and age-related changes in blood pressure in the US population: analysis of NHANES III.

    Archives of internal medicine·2001

    Area of Science:

    • Cardiovascular Medicine
    • Nephrology
    • Vascular Surgery

    Background:

    • Renal artery stenosis (RAS) is a significant cause of secondary hypertension.
    • Treatment options for RAS include surgical intervention and percutaneous transluminal angioplasty (PTA).
    • The long-term efficacy and safety of these interventions depend on the underlying etiology of the stenosis.

    Purpose of the Study:

    • To evaluate the long-term blood pressure response to surgical or PTA treatment for renal artery stenosis.
    • To compare the outcomes of treatments based on the etiology of renal artery stenosis (atherosclerotic vs. fibrodysplastic).
    • To assess the impact of these interventions on renal function and patient survival.

    Main Methods:

    • A retrospective analysis of patients who underwent surgery or PTA for renal artery stenosis.

    Related Experiment Videos

  • Blood pressure was measured an average of 3 years post-intervention.
  • Etiology of stenosis (atherosclerotic or fibrodysplastic) and treatment outcomes were recorded.

    • Main Results:

    • 85% of patients with atherosclerotic renal artery stenosis showed blood pressure improvement.
    • The overall cure rate for atherosclerotic RAS was low (6%), suggesting it's often a complication of essential hypertension in smokers.
    • In fibrodysplastic disease, both treatments improved blood pressure, but surgery led to a 41% rate of kidney loss.

    Conclusions:

    • Treatment response for renal artery stenosis is strongly influenced by the lesion's etiology.
    • Angioplasty and surgery can effectively manage blood pressure in atherosclerotic RAS, though rarely curative.
    • While beneficial for blood pressure in fibrodysplastic RAS, surgical risks, including kidney loss, must be considered.