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Evaluation of left ventricular function in obese children without hypertension by a tissue Doppler imaging study

Yazdan Ghandi1, Mehrzad Sharifi2, Danial Habibi3

  • 1Department of Pediatric Cardiology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.

Annals of Pediatric Cardiology
|February 15, 2018
PubMed

Insights

Obese children without hypertension show early signs of cardiac dysfunction, including impaired systolic and diastolic function. Regular monitoring of blood pressure and heart performance is recommended for early detection and management.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Health
  • Obesity Research

Background:

  • Global rise in childhood obesity presents significant health challenges.
  • Cardiac complications in obese adults are known, but data in children are limited.
  • Subclinical cardiac dysfunction in obese children without hypertension is an emerging concern.

Purpose of the Study:

  • To investigate subclinical systolic and diastolic cardiac dysfunction in obese children without hypertension.
  • To compare cardiac function between obese children and healthy controls using echocardiography.
  • To establish the relationship between body mass index (BMI) and cardiac parameters.

Main Methods:

  • Cross-sectional study involving 25 obese children (BMI >30) and 25 healthy children (BMI <25).
  • Comprehensive cardiovascular assessment including ECG and echocardiography with standard, pulsed wave Doppler (PWD), and tissue Doppler imaging (TDI).
  • Statistical analysis using SPSS software (version 24).

Main Results:

  • Obese children exhibited higher resting heart rate and blood pressure, though within normal limits.
  • Significant increases in left ventricular mass, mass index, left atrial-to-aortic diameter ratio, and left ventricular end-diastolic diameter were observed in obese children.
  • PWD and TDI parameters indicated subclinical systolic and diastolic dysfunction, with a positive correlation between isovolumetric relaxation time and BMI.

Conclusions:

  • Childhood obesity, even without hypertension, is linked to subclinical cardiac dysfunction.
  • Echocardiographic evaluation including PWD and TDI is crucial for assessing myocardial performance in obese children.
  • Regular monitoring of blood pressure and cardiac function is recommended for obese children without hypertension.
Abstract

Keywords:
Dopplerechocardiographypediatric obesityventricular dysfunction

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